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Kohki Kawane Selected Research

deoxyribonuclease II (DNASE II)

11/2010Cytokine-dependent but acquired immunity-independent arthritis caused by DNA escaped from degradation.
10/2010Protective targeting of high mobility group box chromosomal protein 1 in a spontaneous arthritis model.
9/2010Interferon-induced TRAIL-independent cell death in DNase II-/- embryos.
11/2008IFN regulatory factor (IRF) 3/7-dependent and -independent gene induction by mammalian DNA that escapes degradation.
10/2006Chronic polyarthritis caused by mammalian DNA that escapes from degradation in macrophages.

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Kohki Kawane Research Topics

Disease

6Arthritis (Polyarthritis)
01/2011 - 10/2006
5Anemia
01/2011 - 01/2005
3Cataract (Cataracts)
06/2014 - 08/2003
3Rheumatoid Arthritis
11/2010 - 10/2006
2Inflammation (Inflammations)
01/2017 - 01/2011
2Neoplasms (Cancer)
06/2014 - 03/2006
1Lymphopenia (Lymphocytopenia)
01/2011
1Cytokine Release Syndrome
11/2010
1Juvenile Arthritis (Juvenile Idiopathic Arthritis)
11/2010
1Systemic Lupus Erythematosus (Libman-Sacks Disease)
03/2010
1Necrosis
10/2006

Drug/Important Bio-Agent (IBA)

9DNA (Deoxyribonucleic Acid)IBA
06/2014 - 08/2003
5deoxyribonuclease II (DNASE II)IBA
11/2010 - 10/2006
2Proteins (Proteins, Gene)FDA Link
01/2017 - 10/2010
2CytokinesIBA
11/2010 - 10/2006
2Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
11/2008 - 10/2006
1Angiopoietin-Like Protein 2IBA
01/2017
1Deoxyribonucleases (DNase)FDA Link
06/2014
1A-Form DNA (A-DNA)IBA
01/2011
1Therapeutic UsesIBA
11/2010
1AntimetabolitesIBA
11/2010
1Methotrexate (Mexate)FDA LinkGeneric
11/2010
1Interleukin-6 (Interleukin 6)IBA
11/2010
1Interferon-betaIBA
01/2005